A pink peptide serum built around Salmon DNA PDRN, a five-peptide complex, niacinamide and adenosine. Analysis snapshot collected 2026-10-26 (Amazon US, New York 10001 delivery context, native USD).
1. Product Information
| Product name | medicube PDRN Pink Peptide Serum with Salmon DNA, Firmer, Even-Looking Skin |
| Brand | medicube |
| ASIN / Model | B0DBF65JYY / 213124 |
| Category path | Beauty & Personal Care > Skin Care > Face > Treatments & Masks > Serums |
| Best Sellers Rank | #52 in Beauty & Personal Care; #3 in Facial Serums |
| Price | $18.90 (list $21.80 per the price tracker, −13.3%; Subscribe & Save $17.01, −10%) |
| Unit price | $18.71 per fl oz (30 ml / 1.01 fl oz) |
| Availability | In Stock; sold by Medicube & Aprilskin |
| Skin types | All |
| Product benefits / scent | Dark Spot Correction / Salmon DNA |
| Item weight / dimensions | 30 g (1.06 oz) / 4.13 × 1.85 × 1.77 in |
| EAN | 8800256108053 |
1.1 What the product is
The medicube PDRN Pink Peptide Serum with Salmon DNA is a 30 ml (1.01 fl oz) lightweight pink facial serum built around Salmon DNA PDRN — printed on the bottle label as PDRN (Sodium DNA) 1% — together with a 5-type peptide complex, niacinamide and adenosine. The listing positions it as a daily-use serum for all skin types, with "Dark Spot Correction" given as the primary product benefit and firmer, more even-looking skin as the headline claim.
The brand's routine map places the serum at the Serum step of its PDRN collection — applied after cleansing and before cream. The texture is described as lightweight and moisturizing, suitable for daily use and all skin types; per the specification table the scent is listed as "Salmon DNA", and the A+ banner says the formula targets dull, tired-looking skin to reveal a plumper, dewier glow.
1.2 Listing bullet points
- Lightweight pink serum with hero actives — Formulated with Salmon DNA PDRN, Niacinamide, and Peptides; suitable for daily use and all skin types.
- Five-peptide + adenosine complex — Formulated with Salmon DNA PDRN, Niacinamide, Peptides, and Adenosine in a lightweight serum suitable for daily skincare routines and all skin types.
- Hydrating formula — Lightweight serum with a moisturizing formula suitable for daily use and all skin types.
- Daily-skincare fit — Formulated for daily skincare and suitable for all skin types.
- PDRN + niacinamide + peptides + adenosine — Contains Salmon DNA PDRN, Niacinamide, Peptides, and Adenosine in a lightweight serum formula.
1.3 Product images

Source: Amazon

Source: Amazon

Source: Amazon
2. Product Rating
| Average rating | 4.6 / 5 |
| Global ratings | 25,837 (star ratings, not written reviews) |
| Quoted US review set | 8 reviews averaging 4.88 / 5 (7 of 8 are 5-star), all Verified Purchase |
| Community aggregator rating | 2.9 / 5 from 30 community reviews (small-sample aggregate; see Ingredient Analysis section for context) |
Rating distribution as rendered on the listing: 83% five-star, 8% four-star; the 1-star bucket (3%) slightly exceeds the 2-star bucket (2%), a thin U-shaped tail that suggests dissatisfaction comes from a small, distinct minority rather than a gradual slide. Shares are rounded; weighted check Σ(stars × share) = 4.6 matches the displayed 4.6.
2.1 Aspect-level sentiment
| Aspect | Mentions | Positive | Negative | Positive share |
|---|---|---|---|---|
| Effectiveness | 1,250 | 1,117 | 133 | 89% |
| Skin appearance | 550 | 500 | 50 | 91% |
| Hydration | 416 | 395 | 21 | 95% |
| Skin softness | 402 | 391 | 11 | 97% |
| Value for money | 372 | 281 | 91 | 76% |
| Texture | 368 | 340 | 28 | 92% |
| Skin irritation | 308 | 127 | 181 | 41% |
| Skin improvement | 282 | 216 | 66 | 77% |
Reading the table: Effectiveness dominates with 1,250 mentions. Every aspect except one sits above 50% positive; Skin irritation is the single inverted theme at 41% positive across 308 mentions — the only credible risk signal on this listing. Aspect mentions overlap, so rows are not additive.
Positive share by aspect (%). Skin irritation is the only aspect below 50% positive.
A separate "Customers liked" module was not rendered for this listing at capture time, so it is omitted rather than reconstructed; the positive side of the sentiment picture is covered by the aspect table above and the reviews in section 4.
3. Ingredient Analysis
This section merges two independent community ingredient databases into one view: a complete 40-ingredient table with per-ingredient acne / irritant / safety grades, and a claims-and-benefits layer (claim matrix, benefits, concerns, key ingredient groups, community votes). The two sources do not fully agree on the count: database B lists 40 ingredients, database A lists 38. The two extras in database B are Palmitoyl Tetrapeptide-7 and Copper Tripeptide-1, which brings the peptide count to five and matches the bottle label's "5 Types Peptide Complex". The two databases are merged here by INCI name rather than by row number; the two extra peptides carry no database-A grade (treated as not rated). Database B also names position 20 "Parfum" where database A names the same component "Fragrance".
3.1 Claim matrix ("What's inside")
3.2 Benefits (community database)
| Benefit | Description | Ingredients delivering it |
|---|---|---|
| Anti-Aging | Softens lines and helps skin look youthful. | 12 ingredients |
| Hydrating | Boosts hydration and relieves dry, tight skin. | 9 ingredients |
| Scar Healing | Improves the look of marks and scars. | 5 ingredients |
| Barrier Repair | Strengthen and restore your skin's natural barrier. | 5 ingredients |
| Skin Texture | Smooths rough patches and refines texture. | 4 ingredients |
| Redness Reducing | Soothes visible redness and calms irritation. | 3 ingredients |
| Reduces Irritation | Eases discomfort and supports skin resilience. | 2 ingredients |
| Acne Fighting | Fights acne and helps prevent breakouts. | 1 ingredient |
| Brightening | Restores radiance to dull, tired skin. | 1 ingredient |
| Good For Oily Skin | Balances oil and helps reduce shine. | 1 ingredient |
| Reduces Large Pores | Minimizes the look of enlarged pores. | 1 ingredient |
| Dark Spots | Fades dark spots for even skin tone. | 1 ingredient |
Number of ingredients behind each benefit claim. Counts of 1 mean a single ingredient carries the claim and are weak evidence.
3.3 Key ingredient groups
| Group | Mechanism | Size |
|---|---|---|
| Peptides | Supports skin hydration and improves firmness. | 5 ingredients (Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Copper Tripeptide-1, Acetyl Hexapeptide-8) |
| Antioxidants | Shields skin from free radical damage. | 2 ingredients (Ubiquinone, Curcuma Longa Root Extract) |
| Niacinamide | Strengthens, smooths, and brightens skin. | 1 ingredient |
| Hyaluronic Acid | Hydrates by attracting and holding water. | 1 ingredient (Sodium Hyaluronate) |
Community ingredient votes: 24 liked, 12 disliked, 4 mixed or unrated — a weak ingredient-level signal, not a product verdict.
3.4 Formula logic
The formula is a water-based serum: PDRN (Sodium DNA) at 1% anchors the "Salmon DNA" story, paired with a five-peptide complex (Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, the two extra Palmitoyl Tetrapeptide-7 and Copper Tripeptide-1, plus Acetyl Hexapeptide-8), niacinamide, adenosine and salmon-derived supporting materials (Salmon Egg Extract, Hydrolyzed Collagen, Atelocollagen). Texture and slip come from glycerin, butylene glycol, dipropylene glycol, glycereth-26 and caprylyl glycol, held in an acrylate / polyisobutene emulsion (Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Polyisobutene, Acrylates/C10-30). Isopropyl Myristate and Sorbitan Oleate are the emollient / emulsifying lipids — both flagged for comedogenicity. The pink colour comes from Cyanocobalamin (vitamin B12), not artificial dye. Tromethamine is the pH adjuster, and a botanical / marine supporting cast (Curcuma Longa, Melia Azadirachta leaf and flower, Ocimum Sanctum, Corallina Officinalis, Milt Extract) rounds it out. The claim matrix confirms no added drying alcohol, silicone, sulfate or paraben; the only fragrance is the listed Parfum / Fragrance.
3.5 Concern flags
| Concern | Explanation (class-level warning) |
|---|---|
| May Trigger Acne | Can clog pores or trigger breakouts — consistent with the pore-clogger flag on Isopropyl Myristate and Sorbitan Oleate. |
| May Worsen Eczema | May worsen itching or irritation for eczema-prone skin. Triggers vary between individuals; work with a dermatologist. |
| May Worsen Oily Skin | May increase shine or excess oil. Triggers vary between individuals. |
| May Worsen Rosacea | Can trigger flare-ups in rosacea-prone skin. Triggers vary between individuals. |
These are ingredient-class warnings ("this formula contains ingredients capable of..."), not a verdict on the product or on any individual. The Skin irritation aspect (41% positive) and the mixed irritation experiences in the review set (section 4) are the only real-world corroboration.
3.6 Safety classification tally
Classifying the 40 ingredients by their database-A safety grade (an inverse metric: grade 1 = lowest caution; ranges judged on the upper bound; a dash means not rated, which is missing data, not a clean bill):
Safety grade distribution across the 40 ingredients. 29 of 40 (72.5%) sit at grade 1, the lowest-caution level; only Fragrance / Parfum (grade 4) is individually flagged. Acne and irritant grades are rated on only a minority of rows — 7 acne-rated and 6 irritant-rated per database A — with two flagged rows: Isopropyl Myristate (acne 5, irritant 3) and Sorbitan Oleate (acne 3). Three ingredients are not rated (Milt Extract and the two database-B-only peptides).
3.7 Complete merged ingredient list (40 / 40)
Function shown as database A · database B. Acne/Comedogenic and Irritant columns show database A · database B ratings (read low = safer, 0 = no known risk; "–" = not rated, never treated as zero). Safety is the database A grade (read low = safer; inverse metric). The two databases are merged by INCI name; rows 36–37 exist only in database B and carry no database-A grade.
| # | Ingredient | Function (A · B) | Acne / Comedo (A · B) | Irritant (A · B) | Safety (A) |
|---|---|---|---|---|---|
| 1 | Water | Solvent · Skin Conditioning | – · – | – · – | 1 |
| 2 | Glycerin | Solvent, Viscosity Control, Skin conditioning, Moisturizer · Humectant | 0 · 0 | 0 · 0 | 1-2 |
| 3 | Dipropylene Glycol | Solvent, Moisturizer · Humectant | – · – | – · – | 1 |
| 4 | Isopropyl Myristate | Solvent, Synthetic ester · Emollient | 5 · 3-5 | 3 · 3 | 1 |
| 5 | Glycereth-26 | Moisturizer · Humectant | 0 · 0 | – · – | 1-2 |
| 6 | Niacinamide | Skin conditioning · Smoothing | – · – | – · – | 1 |
| 7 | 1,2-Hexanediol | Solvent · Skin Conditioning | – · – | – · – | 1 |
| 8 | Sodium DNA | Skin conditioning · Skin Conditioning | – · – | – · – | 1 |
| 9 | Butylene Glycol | Solvent, Fragrance, Viscosity Control, Skin conditioning, Moisturizer · Humectant | 1 · 1 | 0 · 0 | 1 |
| 10 | Polyglycerin-3 | Moisturizer · Humectant | – · – | – · – | 1 |
| 11 | Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer | Viscosity Control · Emulsion Stabilising | – · – | – · – | 1 |
| 12 | Polyisobutene | Viscosity Control · – | – · – | – · – | 1 |
| 13 | Acrylates/C10-30 Alkyl Acrylate Crosspolymer | Viscosity Control · Emulsion Stabilising | – · – | – · – | 1-2 |
| 14 | Milt Extract | Skin conditioning · Skin Conditioning | – · – | – · – | – |
| 15 | Tromethamine | pH Adjusters · Buffering | – · – | – · – | 1-3 |
| 16 | Glyceryl Acrylate/Acrylic Acid Copolymer | Viscosity Control, Moisturizer · Humectant | – · – | – · – | 1 |
| 17 | Pvm/Ma Copolymer | Antistatic · Emulsion Stabilising | – · – | – · – | 1 |
| 18 | Ethylhexylglycerin | – · Skin Conditioning | – · – | – · – | 2 |
| 19 | Capryl Glycol | Moisturizer, Emollient · Emollient | – · – | – · – | 1 |
| 20 | Parfum (Fragrance) | Fragrance · Masking | – · – | – · – | 4 |
| 21 | Melia Azadirachta Leaf Extract | Skin conditioning · Skin Conditioning | – · – | – · – | 1 |
| 22 | Adenosine | – · Skin Conditioning | – · – | – · – | 1 |
| 23 | Caprylyl/Capryl Glucoside | Surfactant · Cleansing | – · – | – · – | 1-2 |
| 24 | Sorbitan Oleate | Emulsifier · Emulsifying | 3 · 3 | 0 · 0 | 1 |
| 25 | Melia Azadirachta Flower Extract | Skin conditioning · Skin Conditioning | – · – | – · – | 1 |
| 26 | Sodium Hyaluronate | Skin conditioning, Moisturizer · Humectant | 0 · 0 | 0 · 0 | 1 |
| 27 | Disodium EDTA | Viscosity Control · Chelating | – · – | – · – | 2 |
| 28 | Curcuma Longa Root Extract | Fragrance · Antioxidant | – · – | – · – | 1 |
| 29 | Cyanocobalamin | Skin conditioning · Skin Conditioning | – · – | – · – | 1 |
| 30 | Hydrolyzed Collagen | Antistatic, Moisturizer, Emollient · Emollient | 0 · – | 0 · – | 1 |
| 31 | Ubiquinone | Antioxidant · Antioxidant | – · – | – · – | 1 |
| 32 | Ocimum Sanctum Leaf Extract | Skin conditioning · Skin Conditioning | – · – | – · – | 1 |
| 33 | Corallina Officinalis Extract | Skin conditioning · Skin Conditioning | – · – | – · – | 1 |
| 34 | Palmitoyl Pentapeptide-4 | Moisturizer · Skin Conditioning | – · – | – · – | 1 |
| 35 | Palmitoyl Tripeptide-1 | Skin conditioning · Skin Conditioning | – · – | – · – | 1 |
| 36 | Palmitoyl Tetrapeptide-7 | – · Skin Conditioning | – · – | – · – | – |
| 37 | Copper Tripeptide-1 | – · Skin Conditioning | – · – | – · – | – |
| 38 | Acetyl Hexapeptide-8 | Skin conditioning, Moisturizer · Humectant | – · – | – · – | 1 |
| 39 | Salmon Egg Extract | – · – | – · – | – · – | 1 |
| 40 | Atelocollagen | Skin conditioning · Skin Conditioning | – · – | – · – | 1 |
Flagged ingredients: Isopropyl Myristate (acne 5 / 3-5, irritant 3 — the single highest comedogenic risk in the formula), Sorbitan Oleate (acne 3) and Parfum / Fragrance (safety grade 4). The PDRN (Sodium DNA) hero active sits at position 8 with no rated risk. Database grades are aggregated community references, not regulatory conclusions.
4. User Reviews & Real-Life Photos
8 US reviews were captured, all marked "Verified Purchase". Reviewer identities (names, handles, profile links) are withheld by policy; each entry carries only rating, review text and date.
4.1 Reading the review set
Recurring positives: hydration and glow dominate — multiple reviewers describe skin that feels "deeply hydrated", "plump", "dewy" and visibly more radiant, with smooth, non-sticky absorption and clean layering under moisturizer, SPF and (for some) makeup. Two reviewers set up a Subscribe & Save reorder or repurchased after finishing a bottle; one perimenopausal reviewer reports her hyperpigmentation, pores and fine lines all improved over two months. The 4-star medical-aesthetician review is the most analytical: it confirms the pink colour is vitamin B12 (not dye), notes the formula is a supportive serum rather than an injectable PDRN treatment, and flags that oily-skin users may prefer Medicube's Ultra Light version.
Recurring complaints: skin irritation is the fault line that the aspect table already flagged. Reviewer #8 says it is "a bit sticky until it dries down" and notes a light scent that she reads as a natural ingredient fragrance (consistent with the Parfum / Fragrance flag — the product is not fragrance-free). The aspect-level "Skin irritation" theme sits at only 41% positive; Amazon's own summary notes mixed experiences, with some users reporting breakouts. No reviewer reported a hard allergic reaction, but the irritation signal is real and uneven.
4.2 Real-life customer photos

Source: Amazon

Source: Amazon

Source: Amazon

Source: Amazon
The listing exposed 4 buyer-uploaded image tiles (videos excluded); the four above are reproduced. No reviewer identity is attached to any photo.
5. Price Analysis
5.1 Current pricing (Amazon US, capture 2026-10-26)
| Current selling price | $18.90 (buy box, US delivery context) |
| Unit price | $18.71 per fluid ounce |
| Subscribe & Save | $17.01 (−10% subscription tier) |
| List price | $21.80 (per the price tracker; not shown as a struck-through reference on the live listing) |
| Best unit price | $17.01 ÷ 1.01 fl oz ≈ $16.84 / fl oz on subscription |
5.2 Long-run price history (all-time, since monitoring began Nov 19, 2024)
| Price Type | Lowest Ever | Highest Ever | Current | Average |
|---|---|---|---|---|
| Amazon | $16.79 (Jul 26, 2026) | $20.97 (Sep 11, 2026) | – | $18.18 |
| 3rd Party New | $11.99 (May 05, 2025) | $39.90 (Jan 22, 2025) | $18.90 (Oct 08, 2026) | $17.61 |
| 3rd Party Used | – | – | – | – |
The empty "Amazon current" cell is a finding (no active "Sold by and shipped by Amazon" offer is recorded), not a gap: the live $18.90 buy box observed on Amazon on 2026-10-26 is being fulfilled under the 3rd Party New series. "3rd Party Used" has no data at all. The $18.90 current value is dated Oct 08, 2026 — a last-observation value, about 18 days stale, below the 30-day re-verify threshold. All figures below are all-time statistics, not period statistics.
Price comparison from the history table ($): Lowest Ever, Highest Ever, Current and Average for the Amazon and 3rd Party New channels. The Amazon "Current" bar is omitted (no current Amazon-sold offer on record).
5.3 Derived metrics (computations, not source figures)
| Benchmark | Value | Current $18.90 vs benchmark |
|---|---|---|
| All-time low (3rd Party New) | $11.99 (May 05, 2025) | +57.6% |
| All-time high (3rd Party New) | $39.90 (Jan 22, 2025) | −52.6% |
| All-time average (3rd Party New) | $17.61 | +7.3% |
| List price | $21.80 | −13.3% |
| Price type | Spread (high − low) | Spread % of low | Average | Average vs list $21.80 |
|---|---|---|---|---|
| Amazon | $4.18 | 24.9% | $18.18 | −16.6% |
| 3rd Party New | $27.91 | 232.8% | $17.61 | −19.2% |
Channel comparison (derived): the 3rd Party New average has run $0.57 below the Amazon average; both long-run averages sit meaningfully below the $21.80 list, so the list price reads as a reference anchor rather than a typical street price. The 3rd Party New spread is dominated by a single launch-era $39.90 high (Jan 22, 2025); excluding that outlier, the channel band would be far tighter (inference).
5.4 Timeline of dated extremes
| Date | Event |
|---|---|
| Nov 19, 2024 | Price monitoring begins |
| Jan 22, 2025 | 3rd Party New all-time high $39.90 (launch-era outlier) |
| May 05, 2025 | 3rd Party New all-time low $11.99 |
| Jul 26, 2026 | Amazon all-time low $16.79 |
| Sep 11, 2026 | Amazon all-time high $20.97 |
| Oct 08, 2026 | 3rd Party New current $18.90 (last observation) |
Interpretation (inferential): the $39.90 high is a launch-era outlier (January 2025, one month after monitoring began) that inflates the 3rd Party New spread and pulls its average up; the operating band since is far narrower. The current $18.90 sits 13.3% below list and 7.3% above the 3rd Party New long-run average — a normal operating position for this listing.
6. Methodology, Confidence and Limitations
6.1 Collection method
- Product, rating and review data: Amazon.com US product detail page for ASIN B0DBF65JYY, captured 2026-10-26 in a US delivery context (New York 10001), native USD, no currency conversion. Reviews come from the page's inline review block; the standalone review endpoint is walled, so only the default-ranked first page is available.
- Ingredient data: two independent community ingredient databases, captured the same week; database B lists 40 ingredients, database A lists 38 (the two extra peptides in B match the bottle's "5 Types Peptide Complex"). The two were merged by INCI name. Database A provides acne/irritant/safety grades; database B provides claims, benefits, concerns and community votes.
- Price history: a public Amazon price-tracking service, all-time summary block; period-specific statistics are not obtainable from this source and none are presented.
- Anonymisation: reviewer names, handles, profile URLs and avatars are discarded; reviews are labelled "Reviewer #N" and any self-identifying details in quoted text are retained only where they describe skin conditions, not identity.
6.2 Confidence by field
| Field | Confidence | Rationale |
|---|---|---|
| Title, brand, category, specs | High | Read from the listing's labelled nodes |
| Rating, count, distribution | High | All five histogram buckets present, sum to 100%, weighted check matches |
| Current price | High | Single unambiguous buy-box price in a US context |
| List price | Medium | Read from the price tracker, not shown struck-through on the live listing |
| Price history | High for values; Medium for "current" freshness | Verbatim from the tracker; the current observation is ~18 days old |
| Ingredient list and merge | High (counts); Medium (cross-database name match) | Two databases compared row by row by INCI name; one naming divergence (Parfum / Fragrance) |
| Ingredient grades | Medium | Community aggregates; 7 acne-rated and 6 irritant-rated rows in database A |
| Claims matrix / benefits / concerns | Medium | Single aggregator's derivation; class-level warnings, not product verdicts |
| Top US reviews | High for the 8 quoted; low for representativeness | Default-ranked page-1 subset, not a random sample |
| Customers liked | Not available | Module not rendered for this listing |
6.3 Limitations
- Point-in-time snapshot. Price, rank, rating counts and availability change continuously; figures are as of 2026-10-26.
- Ratings ≠ reviews. The 25,837 figure counts star ratings, not written reviews.
- Review sampling. Only page 1 of reviews is available; the quoted set is a default-ranked subset.
- Delivery-location dependency. Price and availability reflect a US delivery address; other addresses may see a different price or no offer.
- Ingredient grades are references, not compliance conclusions. Community databases are not regulatory sources; "not rated" is missing data, not safety.
- Price history is all-time only with no observation-level series; the shape of the price curve between dated extremes is unknown.
- Formula versions. Ingredient lists reflect the currently indexed formula; production runs and regions can differ. The two databases disagree by two peptides, suggesting both formulas may be in circulation during a reformulation window.
Report generated 2026-10-26. All prices in USD, no conversion applied. Reviewer identities withheld by policy. Product photos and customer photos: Source: Amazon.